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    We set a value of 3.5 kJ/mol for the interaction of PEO with water (the same value as for N0), resulting in a hydration free energy of 14.73 ± 0.05 kJ/mol, which is 5.5 kJ/mol higher than the experimental value.

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    The EU Cosmetics Regulation stipulates that all cosmetics products must be manufactured in accordance with the harmonised standards laid out in GMP, in turn described in the Official Journal of the European Union. GMP ensures that products are prepared in a clean environment and that the products are not contaminated in production.

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